Eric Clapton and Steve Winwood (2009)

When the members of Cream - the indelible '60s hard rock trio whose bluesy psychedelics would influence the music industry for decades to come - parted ways in 1968 due to the irreconcilable egos of bassist Jack Bruce and drummer Ginger Baker, guitarist Eric Clapton joined forces with Traffic frontman Steve Winwood (on sabbatical from his own volatile musicians) to create Blind Faith, a short-lived experimental endeavor born out of jam sessions in Clapton's basement. Sadly, their 1969 collaboration would only produce a single album: a self-titled, six-song record cursed with a risquй cover (depicting a naked preteen) that generated quite a bit of controversy. After a short summer tour, the band dissolved, leaving the two artists with little choice but to go their own separate ways. Winwood returned to Traffic for five years (having failed to keep Blind Faith going, sans Clapton) before tackling a successful solo venture. Clapton carved out a niche for himself as well, dominating the '70s and '80s with numerous hits and a variety of dream projects. While the two remained friends over the years, it wasn't until February of 2008, nearly forty years after Blind Faith's breakup, that Winwood and Clapton would find time to come together again.